PICQUET Michel Voir la fiche profil en français Français (FR)

image-profil
  • PICQUET Michel
  • Statut : Assistant Professor
  • Team : OCS
  • Function : Researchers
  • Second team : Search support
  • Function in second team : Technical and IT staff
  • Tags : Bio(in)organic chemistry, Coordination chemistry
  • ORCID : 0000-0002-4532-2404
  • Address :

    ICMUB Institut de Chimie Moléculaire de l'Université de Bourgogne
    Bât. MIRANDE - Aille B - Bureau 220
    9 Avenue Alain Savary
    21000 Dijon – France

  • Tél : +33 380 393 773
  • Michel.Picquet@u-bourgogne.fr

- 2017 – ... : Director of the Plateforme d’Analyse Chimique et de Synthèse Moléculaire de l’Université de Bourgogne
- 2000 – 2017 : vice-director of the Plateforme d’Analyse Chimique et de Synthèse Moléculaire de l’Université de Bourgogne
- 1999 – ... : Assistant Professor at Université de Bourgogne
- 1998 – 1999 : post-doctoral fellowship, Prof R. Sheldon, Technological University of Delft (The Netherlands)
- 1995 – 1998 : European PhD, Université de Rennes I, Prof. P. H. Dixneuf and Dr. C. Bruneau  

- Synthesis and evaluation of novel organometallic anti-cancer agents
- Catalytic activation of small molecules by coordination complexes
- In parallel to my teaching and research duties, I have been in charge of the vice-direction of the Plateforme d'Analyse Chimique et de Synthèse Moléculaire de l'Université de Bourgogne (PACSMUB), the analytical platform of the Institut de Chimie Moléculaire de l’Université de Bourgogne (ICMUB), over the period 2003-2017. Since 2017 I have been promoted Director of this platform which gathers the analytical equipments of the Institut (approx. 7 M€). Since 2010 the platform is open to external entities, under the name Pôle Chimie Moléculaire Sayens (ISO9001) and offers analytical and expertise services to other universities and private companies through the SATT SAYENS. 

52 publication, 1821 citations (Web of Knowledge 27/02/2018), h-index: 28
2 patents, 1 Soleau envelop

52. Trommenschlager, A.; Chotard, F.; Bertrand, B.; Amor, S.; Dondaine, L.; Picquet, M.; Richard, P.; Bettaïeb, A.; Le Gendre, P.; Paul, C.; Goze C.; Bodio, E., “Gold(I)-BODIPY-imidazole bimetallic complexes as new potential anti-inflammatory and anticancer trackable agents”, Dalton Trans., 2017, 46, 8051-8056.
51. Wenzel, M.; de Almeida, A.; Bigaeva, E.; Kavanagh, P.; Picquet, M.; Le Gendre, P.; Bodio, E. ; Casini, A., “New Luminescent Polynuclear Metal Complexes with Anticancer Properties: Toward Structure-Activity Relationships”, Inorg. Chem., 2016, 55, 2544-2557.
49. (book chapter) Bodio, E.; Picquet, M.; Le Gendre, P., “Early-late heterometallic catalysis and beyond”, Top. Organomet. Chem., 2016, 59, 139-186.
48. Laurenczy, G.; Dalebrook, A. F.; Picquet, M.; Plasseraud, L., “High-Pressure NMR spectroscopy: A, in situ tool to study tin-catalyzed synthesis of organic carbonates from carbon dioxide and alcohols”, J. Organomet. Chem., 2015, 796, 53-58.
47. Baraut, J.; Massard, A.; Chotard, F.; Bodio, E.; Picquet, M.; Richard, P.; Borguet, Y.; Nicks, F.; Demonceau, A.; Le Gendre, P., “Assessment of Catalysis by Arene-Ruthenium Complexes Containing Phosphane or NHC Groups bearing Pendant Conjugated Diene Systems”, Eur. J. Inorg. Chem., 2015, 16, 2671-2682.
46. Bertrand, B.; Spreckelmeyer, S.; Bodio, E.; Cocco, F.; Picquet, M.; Richard, P.; Le Gendre, P.; Orvig, C.; Cinellu, M. A.; Casini, A., “Exploring the potential of gold(III) cyclometallated compounds as cytotoxic agents: variations on the CN theme”, Dalton Trans., 2015, 44, 11911-11918.
45. Bertrand, B.; Spreckelmeyer, S.; Bodio, E.; Cocco, F.; Picquet, M.; Richard, P.; Le Gendre, P.; Orvig, C.; Cinellu, M. A.; Casini, A., “Exploring the potential of gold(III) cyclometallated compounds as cytotoxic agents: variations on the CN theme”, Dalton Trans., 2015, 44, 11911-11918.
44. Bertrand, B.; Bodio, E.; Richard, P.; Picquet, M.; Le Gendre, P.; Casini, A., “Gold(I) N-heterocyclic carbene complexes with an "activable" ester moiety: Possible biological applications”, J. Organomet. Chem., 2015, 775, 124-129.
43. Wenzel, M.; Bigaeva, E.; Richard, P.; Le Gendre, P.; Picquet, M.; Casini, A.; Bodio, E., “New heteronuclear gold(I)-platinum(II) complexes with cytotoxic properties: Are two metals better than one?”, J. Inorg. Biochem., 2014, 141, 10-16.
42. Normand, A. T.; Massard, A.; Richard, P.; Canovas, C.; Balan, C.; Picquet, M.; Auffrant, A.; Le Gendre. P., “Titanium imido complexes stabilised by bis(iminophosphoranyl)methanide ligands: the influence of N-substituents on solution dynamics and reactivity”, Dalton Trans., 2014, 43, 15098-15110.
41. Bertrand, B.; de Almeida, A.; van der Burgt, E. P. M.; Picquet, M.; Citta, A.; Folda, A.; Rigobello, M. P.; Le Gendre, P.; Bodio, E. ; Casini, A., “New Gold(I) Organometallic Compounds with Biological Activity in Cancer Cells”, Eur. J. Inorg. Chem., 2014, 27, 4532-4536.
40. Adriaenssens, L.; Liu, Q.; Chaux-Picquet, F.; Tasan, S.; Picquet, M.; Denat, F.; Le Gendre, P.; Marques, F. ; Fernandes, C. ; Mendes, F. ; Gano, L. ; Campello, M. P. C. ; Bodio, E. ; Casini, A., “Novel Heterobimetallic Radiotheranostic: Preparation, Activity, and Biodistribution”, ChemMedChem., 2014, 9, 1567-1573.
39. Bertrand, B.; Stefan, L.; Pirotta, M.; Monchaud, D.; Bodio, E.; Richard, P.; Le Gendre, P.; Warmerdam, E. ; de Jager, M. H.. ; Groothuis, G. M. M.. ; Picquet, M. ; Casini, A., “Caffeine-Based Gold(I) N-Heterocyclic Carbenes as Possible Anticancer Agents: Synthesis and Biological Properties”, Inorg. Chem., 2014, 53, 2296-2303.
38. Picquet, M., “Organometallics as catalysts in the fine chemical industry.”, book review, Platinum Metals Rev., 2013, 57, 272-280.
37. Hierso, J.-C.; Beauperrin, M.; Saleh, S.; Job, A.; Andrieu, J.; Picquet, M., "Uncommon perspectives in palladium- and copper-catalysed arylation and heteroarylation of terminal alkynes following Heck or Sonogashira protocols: Interactions copper/ligand, formation of diynes, reaction and processes in ionic liquids.”, C. R. Chimie. 2013, 16, 580-596.
36. Tasan, S.; Zava, O.; Bertrand, B.; Bernhard, C.; Goze, C.; Picquet, M.; Le Gendre, P.; Harvey, P. D.; Denat, F.; Casini, A.; Bodio, E., “BODIPY-phosphane as a versatile tool for easy access to new metal-based theranostics.”, Dalton Trans. 2013, 42, 6102-6109.
35. Assémat, E.; Attard, L.; Penouilh, M.-J.; Picquet, M.; Tabard, A.; Zhang, Y.; Glaser, S. J.; Sugny, D., "Optimal control of the inversion of two spins in Nuclear Magnetic Resonance.”, Chem.Phys. 2012, 405, 71-75.
34. Rampazzi, V.; Massard, A.; Richard, P.; Picquet, M.; Le Gendre, P.; Hierso, J.-C., “ A simple phosphine-diolefin promotes copper-catalysed N-arylation of pyrazoles with (hetero)aromatic bromides: the case of chloroarenes revisited.”, ChemCatChem. 2012, 11, 1828-1835.
33. Stefan, L.; Bertrand, B.; Richard, P.; Le Gendre, P.; Denat, F.; Picquet, M.; Monchaud, D., “Assessing the differential affinity of small-molecules for nonusual DNA structures.”, ChemBioChem. 2012, 13, 1905-1912.
32. Naik, P. U.; Refes, K.; Sadaka, F.; Brachais, C.-H.; Boni, J.; Couvercelle, J.-P.; Picquet, M.; Plasseraud, L., "Organo-catalyzed synthesis of aliphatic polycarbonates in solvent-free conditions.", Polymer Chem. 2012, 3, 1475-1480.
31. Massard, A.; Rampazzi, V.; Perrier, A.; Bodio, E.; Picquet, M.; Richard, P.; Hierso, J.-C.; Le Gendre, P., "(Cycloheptadienyl)diphenylphosphine: A Versatile Hybrid Ligand.", Organometallics 2012, 31, 947-958.
30. Harmand, L.; Saleh, S.; Andrieu, J.; Cattey, H.; Picquet, M.; Hierso, J.-C., “Linear Triphosphines as Ligands for Metal Complexes Immobilization in Ionic Liquids: Palladium-Catalyzed Methoxylation of Alkynes.”, Open Org. Chem. J. 2012, 6, 1-11.
29. Saleh, S.; Picquet, M.; Meunier, P.; Hierso, J.-C., “Double Arylation of Diynes and Alkynylation of Functionalized Heteroaryl Halides by a Practical Heck Reaction in an Ionic Liquid.”, Synlett 2011, 696, 2844-2848.
28. Wenzel, M.; Bertrand, B.; Eymin, M.-J.; Comte, V.; Harvey, J. A.; Richard, P.; Groessl, M.; Zava, O.; Amrouche, H.; Harvey, P. D.; Le Gendre, P.; Picquet, M.; Casini, A., “Multinuclear Cytotoxic Metallodrugs: Physicochemical Characterization and Biological Properties of Novel Heteronuclear Gold_Titanium Complexes.”, Inorg. Chem. 2011, 50, 9472-9480.
27. Laurenczy, G.; Picquet, M.; Plasseraud, L., “Di-n-Butyltin(IV)-Catalyzed Dimethyl Carbonate Synthesis From Carbon Dioxide And Methanol: An In Situ High Pressure 119Sn{1H} NMR Spectroscopic Study.”, J. Organomet. Chem. 2011, 696, 1904-1909.
26. Pelletier, F.; Comte, V.; Massard, A.; Wenzel, M.; Toulot, S.; Richard, P.; Picquet, M.; Le Gendre, P.; Zava, O.; Edafe, F.; Casini, A.; Dyson, P. J., “Development of bimetallic titanocene-ruthenium-arene complexes as anticancer agents: relationships between structural and biological properties.”, J. Med. Chem. 2010, 53, 6923-6933.
25. Vorotyntsev M. A., Zynovieva V. A., Picquet M., “Diffusional transport in ionic liquids: Stokes-Einstein relation or "sliding sphere" model? Ferrocene (Fc) in imidazolium liquids”, Electrochim. Acta 2010, 55, 5063-5070.
24. Georg S., Billard I., Ouadi A., Gaillard C., Petitjean L., Picquet M., Solov’ev V., “Determination of Successive Complexation Constants in an Ionic Liquid: Complexation of UO22+ with NO3- in C4-mimTf2N Studied by UV-vis Spectroscopy”, J. Phys. Chem. B 2010, 114, 4276-4282.
23. Andrieu J., Harmand L., Picquet M., “Firsts Lysidinyl- and Lysidinium-triphosphines Pd(II) complexes”, Polyhedron 2010, 29, 601-605.
22. Saleh S., Picquet M., Meunier P., Hierso J.-C., “A straightforward copper-free palladium methodology for the selective alkynylation of a wide variety of S-, O-, and N-based mono- and diheterocyclic bromides and chlorides”, Tetrahedron 2009, 65, 7146-7150.
21. Naik P. U., Petitjean L., Refes K., Picquet M., Plasseraud L., “Imidazolium-2-Carboxylate as an Efficient, Expeditious and Eco-Friendly Organocatalyst for Glycerol Carbonate Synthesis”, Adv. Synth. Catal. 2009, 351, 1753-1756.
20. Saleh S., Fayad E., Azouri M., Hierso J.-C., Andrieu J., Picquet M., “Donor stabilized-phosphenium adducts as new efficient and immobilizing ligand in Pd-Alkynylation and Pt-Hydrogenation in ionic liquids”, Adv. Synth. Catal. 2009, 351, 1621-1628.
19. Azouri M., Andrieu J., Picquet M., Cattey H., “Synthesis of new cationic donor stabilized phosphenium adducts and their unexpected P substituents exchange reactions”, Inorg. Chem. 2009, 48, 1236-1242.
18. Vorotyntsev M. A., Zynovieva V. A., Konev D. V., Picquet M., Gaillon L., Rizzi C., “Electrochemical and spectral properties of ferrocene (Fc) in ionic liquid: 1-butyl-3-methylimidazolium triflimide, [BMIM][NTf2]. Concentration effects”, J. Phys. Chem. B 2009, 113, 1085-1099.
17. Azouri M., Andrieu J., Picquet M., Richard Ph., Hanquet B., Tkatchenko I., “Straightforward synthesis of donor stabilized-phosphenium adducts from imidazolium-2-carboxylate and their electronic properties”, Eur. J. Inorg. Chem. 2007, 4877-4883.
16. Hierso J.-C., Boudon J., Picquet M., Meunier P., “The First Catalytic Method for Heck Alkynylation of Unactivated Aryl Bromides (Copper-Free Sonogashira) in an Ionic Liquid: 1 mol-% Palladium/Triphenylphosphane/Pyrrolidine in [BMIM][BF4] as a Simple, Inexpensive and Recyclable System”, Eur. J. Org. Chem., 2007, 583-587.
15. Hierso J.-C., Picquet M., Cattey H., Meunier P., “Palladium-Catalyzed Heck Alkynylation of Aryl Bromides in an Imidazolium Ionic Liquid: An Unexpected Subsequent Hydrogenation Reaction”, Synlett, 18, 2006, 3005-3008.
14. Tkatchenko I., Picquet M., Poinsot D., Tommasi I., Wasserscheid P., Zimmermann J., “Ionic liquids 4. Ionic Liquids: Media for Better Molecular Catalysis”, Topics in Catalysis, 2004, 29, 139-143.
13. Picquet M., Tkatchenko I., Tommasi I., Zimmermann J., Wasserscheid P., "Ionic liquids. 2. Hydrogenoimidazolium salts: bifunctional media for molecular catalysis”, Adv. Synth. Catal., 2003, 345, 959-962.
12. Ballivet-Tkatchenko D., Picquet M., Solinas M., Franció G., Wasserscheid P., Leitner W., "Acrylate dimerisation under ionic liquid-supercritical carbon dioxide conditions“, Green Chem., 2003, 232-235.
11. Picquet M., Stutzmann S., Tkatchenko I., Tommasi I., Zimmermann J., Wasserscheid P., "Selective palladium-catalysed dimerisation of methyl acrylate in ionic liquids: towards a continuous process“, Green Chem., 2003, 153-162.
10. Le Gendre P., Picquet M., Richard Ph., Moïse C., "Ti-Ru bimetallic complexes: catalysts for ring-closing metathesis“, J. Organomet. Chem., 2002, 643-644, 231-236.
9. Osipov S. N., Artyushin O. I., Kolomiets A. F., Bruneau C., Picquet M., Dixneuf P. H., "Synthesis of fluorine-containing cyclic alpha-amino phosphonate derivatives by alkene metathesis“, Eur. J. Org. Chem., 2001, 3891-3897.
8. Picquet M., Fernández A., Bruneau C., Dixneuf P. H., "Efficient ruthenium-catalysed synthesis of 3 hydroxy-1-propen-1-yl benzoates: en route to an improved isomerization of 2-propyn-1-ols into alpha,beta-unsturated aldehydes“, Eur. J. Org. Chem., 2000, 2361-2366.
7. Fürstner A., Liebl M., Lehman C. W., Picquet M., Kunz R., Bruneau C., Touchard D., Dixneuf P. H., "Cationic ruthenium allenylidene complexes as catalysts for ring closing metathesis“, Chem. Eur. J., 2000, 6, 1847-1857.
6. Picquet M., Bruneau C., Dixneuf P. H., "Michael additions of carbonucleophiles to butenone catalyzed by the non-hydride [Ru(O2CH)(CO)2(PPh3)]2 complex“, Tetrahedron, 1999, 55, 3937-3948.
5. Picquet M., Touchard D., Bruneau C., Dixneuf P. H., "Room temperature operating allenylidene precatalyst [LnRu=C=C=CR2]+.X- for olefin metathesis: dramatic influence of the counter anion X-", New J. Chem., 1999, 23, 141-143.
4. Picquet M., Bruneau C., Dixneuf P. H., "Catalytic synthesis of 3-vinyl-2,5-duhydrofurans from yne-enes promoted by photochemically activated metal-allenylidene LnRu=C=C=CR2 complex“, Chem. Commun. 1998, 2249-2250.
3. Osipov S. N., Kolomiets A. F., Bruneau C., Picquet M., Dixneuf P. H., "Synthesis of fluorine-containing cyclic amino acid derivatives via ring closing olefin metathesis“, Chem. Commun., 1998, 2053-2054.
2. Fürstner A., Picquet M., Bruneau C., Dixneuf P. H., "Cationic ruthenium allenylidene complexes as a new class of performing catalysts for ring closing metathesis“, Chem. Commun., 1998, 1315-1316.
1 - Picquet M., Bruneau C., Dixneuf P. H., "Selective isomerization of prop-2-yn-1-ols into alpha,beta-unsturated aldehydes catalyzed by Ru[CH2C(Me)CH2]2(Ph2PCH2CH2PPh2)“, Chem. Commun., 1997, 1201-1202.

Patents and Soleau envelops:

3 - Franció G., Solinas M., Janssen E., Leitner W., Bösmann A., Wasserscheid P., Zimmermann J., Ballivet-Tkatchenko D., Picquet M., Stutzmann S., "Method for activating and immobilizing cationic transition metal catalysts using ionic fluids and compressed CO2", PCT Int. Appl., 2002, WO 2002092204
2 - Ballivet-Tkatchenko D., Picquet M., Stutzmann S., Wasserscheid P., Zimmermann J., "Combinaison de Réactions Catalytiques en Milieu Liquides Ioniques avec une Extraction par le Dioxyde de Carbone Supercritique", Soleau envelop 07 9872 (31/07/2000)
1 - Fürstner A., Dixneuf P. H., Bruneau C., Picquet M., Kunz R., "Highly active ruthenium and osmium complexes for olefin metathesis reaction", PCT Int. Appl., 1999, WO 9928330

9 conferences, 17 oral communications, 41 posters